Benadryl is pictured at a home in North Vancouver, B.C., Monday, November, 11, 2019. THE CANADIAN PRESS/Jonathan Hayward

Benadryl is pictured at a home in North Vancouver, B.C., Monday, November, 11, 2019. THE CANADIAN PRESS/Jonathan Hayward

Moving Benadryl behind the counter doesn’t resolve safety concerns: pharmacists

More doctors are warning against older antihistamines, such as the active ingredient in Benadryl

Sally McQuinn once kept her medicine cabinet stocked with Benadryl, the go-to medication to treat her daughter’s multiple allergies: the Ottawa mother of three assumed that because it was sold on pharmacy shelves and didn’t require a prescription, it was safe.

But she was surprised by recent headlines highlighting that a growing number of doctors are warning against the use of older antihistamines, such as diphenhydramine, the active ingredient in Benadryl, because of safety and efficacy concerns.

McQuinn says she will no longer buy Benadryl and instead choose from the number of existing alternatives.

“Nobody wants to choose the one that’s going to have more negative consequences,” she explains.

The Canadian Society of Allergy and Clinical Immunology released a statement in October recommending curbing the use of older first-generation antihistamines in both adults and children. They said newer antihistamines, including Reactine, Aerius, and Claritin, are safer.

Long-known side effects from standard doses of Benadryl include sedation, cognitive impairment, and possible heart rhythm abnormalities.

Children are particularly at risk of severe consequences, such as seizures and coma, from too high a dose, and research suggests teens using Benadryl for allergies have lower scores on exams than their peers.

The CSACI statement called on regulators to consider moving Benadryl and other first-generation antihistamines from pharmacy shelves to behind the counter in order to force an interaction with pharmacists who can explain the issues and suggest alternatives.

Pharmacists, however, say the solution isn’t so simple: putting Benadryl behind the counter, they say, is not practical and won’t resolve the safety concerns. And they have the same concerns about many other over-the-counter drugs.

READ MORE: Canadian allergists’ group wants Benadryl behind the counter due to side effects

Consumers would have to speak to a pharmacist, who could decline to provide the medication. But since the drug is approved by Health Canada and is well known, many consumers, will continue to push for it, says pharmacist Barry Power, a spokesman for the Canadian Pharmacists Association.

That can create conflict at the drugstore, he adds.

“For many people, the side effect profile isn’t a big concern. But if Benadryl were to come on the market today, it might require a prescription, because of the safety profile,” he says.

Benadryl’s maker, Johnson & Johnson says the products are approved by Health Canada and “when used as directed, are safe and effective.”

In a statement, Health Canada said products containing diphenhydramine meet the requirements and regulations of the Food and Drugs Act. It says it is assessing the allergists’ recent statement “to determine if further risk mitigation measures for diphenhydramine-containing products are required.”

The agency says that it continues to monitor scientific and medical information as it evolves and would take action if this information required a change to “the regulatory status of products containing diphenhydramine.”

Currently, Benadryl is approved for sale without a prescription in locations where a pharmacist is present. This means that it can be sold in pharmacies and certain grocery stores, but not in convenience stores or gas stations.

Nardine Nakhla, a pharmacist who teaches at the University of Waterloo in Ontario, says moving all the diphenhydramine-containing drugs behind the counter is “unrealistic … due to the sheer number of products that contain these problematic ingredients.”

Nakhla says there are also many other drugs, besides diphenhydramine, that have similar risk profiles and are available on pharmacy shelves.

Power agrees that the issue of which drugs belong behind the counter “becomes a bigger question as you start looking (at it).”

– Dr. Michelle Ward is a pediatrician at the Children’s Hospital of Eastern Ontario and associate professor at the University of Ottawa

The Canadian Press

Like us on Facebook and follow us on Twitter

Get local stories you won't find anywhere else right to your inbox.
Sign up here

Just Posted

(The Canadian Press)
‘Electric blue’ fentanyl sparks drug alert in Vernon

Interior Health issues alert based on testing; no reports of overdoses linked to specific substance at this time

The Baxter Bridge at the north end of Trinity Valley Road east of Enderby is open to all traffic Sunday, Nov. 22, but will close again Monday, Nov. 23, for more repair work. Monday is expected to be the last full-day closure of the bridge, which was shut down by the Ministry of Transportation to all but foot and light emergency vehicle traffic Nov. 8 due to structural issues. (Morning Star - file photo)
Baxter Bridge near Enderby reopens to all traffic

It’s a 24-hour opening 0f the bridge; last full-day closure is expected on Monday, Nov. 23

Two fibreglass bees were stolen from Vernon’s Planet Bee Honey Farm Nov. 22, 2020. (Facebook)
Thief buzzes off with bee sculptures from Vernon honey farm

Planet Bee lost two bee sculptures Sunday night

This homemade, hand-painted five-foot-high Grinch was taken from an outdoor Christmas display at a home near Fulton Secondary Sunday evening, Nov. 22. (Photo submitted)
Grinch steals Grinch from Vernon Christmas display

Owners saddened by theft of beloved homemade five-foot-high Grinch display from yard near Fulton

Kyle Charles poses for a photo in Edmonton on Friday, Nov. 20, 2020. Marvel Entertainment, the biggest comic book publisher in the world, hired the 34-year-old First Nations illustrator as one of the artists involved in Marvel Voice: Indigenous Voices #1 in August. THE CANADIAN PRESS/Jason Franson
VIDEO: Indigenous illustrator of new Marvel comic hopes Aboriginal women feel inspired

Kyle Charles says Indigenous women around the world have reached out

Join Black Press Media and Do Some Good
Join Black Press Media and Do Some Good

Pay it Forward program supports local businesses in their community giving

B.C. Liberal MLA Shirley Bond questions NDP government ministers in the B.C. legislature, Feb. 19, 2020. (Hansard TV)
Cabinet veteran Shirley Bond chosen interim leader of B.C. Liberals

28-member opposition prepares for December legislature session

Motorists wait to enter a Fraser Health COVID-19 testing facility, in Surrey, B.C., on Monday, November 9, 2020. THE CANADIAN PRESS/Darryl Dyck
COVID-19: What do rising positivity rates mean for B.C.? It’s not entirely clear

Coronavirus cases are on the rise but the province has not unveiled clear thresholds for further measures

A rider carves a path on Yanks Peak Saturday, Nov. 21. Two men from Prince George went missing on the mountain the next day. One of them, Colin Jalbert, made it back after digging out his sled from four feet under the snow. The other, Mike Harbak, is still missing. Local search and rescue teams went out looking Monday, Nov. 23. (Sam Fait Photo)
‘I could still be the one out there’: Snowmobiler rescued, 1 missing on northern B.C. mountain

As Quesnel search and rescue teams search for the remaining rider, Colin Jalbert is resting at home

More than 70 anglers participated in the bar-fishing demonstration fishery on Sept. 9, 2020 on the Fraser River near Chilliwack. DFO officers ticketed six people and seized four rods. A court date is set for Dec. 1, 2020. (Jennifer Feinberg/ Chilliwack Progress file)
Anglers ticketed in Fraser River demonstration fishery heading to court

Sportfishing groups started a GoFundMe with almost $20K so far for legal defence of six anglers

Care home staff are diligent about wearing personal protective equipment when they are in contact with residents, but less so when they interact with other staff members, B.C. Seniors Advocate says. THE CANADIAN PRESS/Chris Young
More COVID-19 testing needed for senior home staff, B.C.’s advocate says

Employees mingling spotted as virus conductor in many workplaces

Penticton RCMP are looking to speak to this woman who allegedly spat on an employee at Skaha Liquor Store as well as dropping his phone on the ground. (Facebook)
WATCH: Unmasked Okanagan woman allegedly spits on employee, drops his phone

Penticton RCMP are looking for the woman who was refused service for not wearing a mask

Jason Townsend, wearing his Kelowna prospect patches. (Jason Townsend Facebook photo)
Trial dates set for two alleged Kelowna Hells Angels associates

Jason Townsend and Colin Michael Bayley will each stand trial on separate matters in May 2021

Most Read